Pitaloosie was born in 1942 on the southwest coast of Baffin Island near what is now the community of Cape Dorset. She spent her childhood years in various hospitals in Quebec and Ontario for treatment of tuberculosis. She learned English during this time, and recalls the difficulty she experienced in relearning her native language upon her return to Baffin Island in 1957. Pitaloosie became one of the few of her generation who spoke both English and Inuktitut fluently.

Pitaloosie began drawing in the early 1960’s, and quickly established herself as a versatile and intelligent graphic artist. Over the years, she became a familiar presence in the Kinngait Studios, with her work included in annual print collections since 1968. Beginning in the late 1960’s, Pitaloosie made frequent trips to southern Canada to attend exhibitions and conferences. In 1967, she spent several weeks in Toronto while her husband, the well-known sculptor Pauta Saila, participated in an International Sculpture Symposium. Subsequently, she visited Halifax, Toronto, Ottawa, Kansas City and Vermont.

Her work has been featured in solo drawing exhibitions, and in 1977, Canada Post issued a stamp depicting her print, Fisherman’s Dream. Saila’s 1985 lithograph entitled In the Hills represented the Northwest Territories in the centennial celebration of the National Parks of Canada. Amnesty International, the international human rights organization, selected a drawing by Pitaloosie entitled Mother and Child to use for their 1990 Christmas card.

She was also one of nine featured artists in the acclaimed exhibition Isumavut: The Artistic Expression of Nine Cape Dorset Women, which opened at the Canadian Museum of Civilization in the fall of 1994 Pitaloosie’s husband, Pauta, passed away in Cape Dorset in June of 2009 at the age of 93. In 2004, both she and Pauta were appointed members of the Royal Canadian Academy of the Arts, in recognition of their life’s work and contributions to Canadian art. Pitaloosie passed away in July of 2021, in Cape Dorset, at the age of 79. 

“I remember how Inuit used to live, thinking of them back then, my relatives. I also recall how the clothing was made; that is what I base my drawings on when I draw people.” - Pitaloosie Saila (from “Kinngait: Riding Light Into the World; Producer: Site Media; Director: Annette Mangaard)